Structure of PDB 6aob Chain B Binding Site BS01

Receptor Information
>6aob Chain B (length=178) Species: 4808 (Blastocladiella emersonii) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AKEYESVTVFFSDITNFTVISSRTSTKDMMATLNKLWLEYDAIAKRWGVY
KVETIGDAYLGVTGAPDVVPDHAERACNFAVDIIEMIKSFKTITGESINI
RIGLNSGPVTAGVLDLNPHWCLVGDTVNTASRMESTSKAGHIHISESTYH
FIKSKFVTQPLDVMEVGKMQTYWVLGRK
Ligand information
Ligand IDMN
InChIInChI=1S/Mn/q+2
InChIKeyWAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mn+2]
CACTVS 3.341[Mn++]
FormulaMn
NameMANGANESE (II) ION
ChEMBL
DrugBankDB06757
ZINC
PDB chain6aob Chain B Residue 701 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6aob Structure and monomer/dimer equilibrium for the guanylyl cyclase domain of the optogenetics protein RhoGC.
Resolution1.7 Å
Binding residue
(original residue number in PDB)		D457 D501
Binding residue
(residue number reindexed from 1)		D13 D57
Annotation score4
Enzymatic activity
Catalytic site (original residue number in PDB) D457 I458 D501 R577
Catalytic site (residue number reindexed from 1) D13 I14 D57 R132
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0009190 cyclic nucleotide biosynthetic process
GO:0035556 intracellular signal transduction

View graph for
Biological Process
External links
PDB RCSB:6aob, PDBe:6aob, PDBj:6aob
PDBsum6aob
PubMed29118188
UniProtA0A060H1D7

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