Structure of PDB 5zt7 Chain B Binding Site BS01

Receptor Information

>5zt7 Chain B (length=252) Species: 224308 (Bacillus subtilis subsp. subtilis str. 168) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

SMKQAILYVGHGSRVKKAQQEAAAFLEGCKAHISVPVQEISFLELQEPTI
ETGFEACVKQGATHIAVVPLLLLTAAHAKHDIPEEIVRVASRYPSVRISY
GKPIGIDEEVVKAVYHRMKDIGVPYENARVVLIGRGSSDPDVKRDVTGIA
NLLQEMVPVKEVIPCFLTACGPNYKEVFSELEKDDGITTFIVPYLLFTGM
LMNEIEREVQKLKAHNPNVYLSSYIGFHPHVKNAFLNRVRETAANSEGQF
DF

Ligand information

Ligand ID

InChI

InChI=1S/Co/q+2

InChIKey

XLJKHNWPARRRJB-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Co+2]
CACTVS 3.341	[Co++]

Formula

Name

COBALT (II) ION

PDB chain

5zt7 Chain B Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

Global view

Local view

Structure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

PDB	5zt7 Structure of sirohydrochlorin ferrochelatase SirB: the last of the structures of the class II chelatase family.
Resolution	2.94 Å
Binding residue (original residue number in PDB)	H31 K231
Binding residue (residue number reindexed from 1)	H32 K232
Annotation score	1

Enzymatic activity

Enzyme Commision number

4.99.1.4: sirohydrochlorin ferrochelatase.

Gene Ontology

	Molecular Function
GO:0016829	lyase activity
GO:0046872	metal ion binding
GO:0051266	sirohydrochlorin ferrochelatase activity

	Biological Process
GO:0006779	porphyrin-containing compound biosynthetic process
GO:0019354	siroheme biosynthetic process

View graph for
Molecular Function

View graph for
Biological Process

External links

PDB	RCSB:5zt7, PDBe:5zt7, PDBj:5zt7
PDBsum	5zt7
PubMed	30778451
UniProt	O34632\|SIRB_BACSU Sirohydrochlorin ferrochelatase (Gene Name=sirB)

[Back to BioLiP]