Structure of PDB 5zov Chain B Binding Site BS01

Receptor Information
>5zov Chain B (length=399) Species: 747 (Pasteurella multocida) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DTTTVIKGTIKTIVGFMIVQAGSGFLVANFKPIIEGLSKYHNLTGAVIDP
YTSMQATIQTMADNYAWVGYAVILALFLNILLVVCRRITGIRTIMLTGHI
MFQQAGLVAVFYMIIGASMWETVIYTAVLMALYWGISSNIMYKPTQAVTG
GAGFSIGHQQQIASWIAVKLAPKLGDKIFHDSISATALVMTVFFGIILLS
KTHWFMYIFEMGLKFAVAIQIIVTGVRMFVAELSEAFKGISERVIPNSVL
AIDCAAIYAFSPNAMVFGFMWGAIGQFVAVGLLLGFSSPILIIPGFIPMF
FSNATIGVFANQFGGWKSVMKICFIMGIIEVLGSAWVIHLLATQGTTFNG
WMGMADWALFFPPILQGIVSIPGFFFVLLTLAIVYMVFASKQLRSEEAA
Ligand information
Ligand IDASC
InChIInChI=1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1
InChIKeyCIWBSHSKHKDKBQ-JLAZNSOCSA-N
SMILES
SoftwareSMILES
CACTVS 3.341OC[CH](O)[CH]1OC(=O)C(=C1O)O
OpenEye OEToolkits 1.5.0C(C(C1C(=C(C(=O)O1)O)O)O)O
OpenEye OEToolkits 1.5.0C([C@@H]([C@@H]1C(=C(C(=O)O1)O)O)O)O
CACTVS 3.341OC[C@H](O)[C@H]1OC(=O)C(=C1O)O
ACDLabs 10.04O=C1OC(C(O)=C1O)C(O)CO
FormulaC6 H8 O6
NameASCORBIC ACID;
Vitamin C
ChEMBLCHEMBL196
DrugBankDB00126
ZINCZINC000100006770
PDB chain5zov Chain B Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5zov Inward-facing conformation of l-ascorbate transporter suggests an elevator mechanism
Resolution3.333 Å
Binding residue
(original residue number in PDB)		Y87 H135 I136 Q139 H194 R288 D314 F362
Binding residue
(residue number reindexed from 1)		Y51 H99 I100 Q103 H158 R227 D253 F301
Annotation score3
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0009401 phosphoenolpyruvate-dependent sugar phosphotransferase system
Cellular Component
GO:0016020 membrane

View graph for
Biological Process
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Cellular Component
External links
PDB RCSB:5zov, PDBe:5zov, PDBj:5zov
PDBsum5zov
PubMed30038796
UniProtQ9CMQ1

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