Structure of PDB 5zl1 Chain B Binding Site BS01

Receptor Information

>5zl1 Chain B (length=306) Species: 247490 (Candidatus Jettenia caeni)

MVDVISNVAKDPADIPGRISRSCPKTVTVNLVAKEVVADLAPGKKFWFWT
FAEKKGDTVGPATVPGPMVRVMEGDTVVINLTNDLHNEEPHNLDFHAGFG
AMLMDIEPGETDTLTFKAKREGAYIYHCGAEGMPWEHVAYGMYGLIVVEP
KGGLSRVDKEFYIGQGEWYIKPGIEDHPHIRGYSLDEDKALAEHPDYFTF
NGHTQALMDPSIYGNAITVNQGDKVRLFFVAGGPNIGSNFHIIGQIFDKF
YPGHRRDFIRNEETAYIPPGSAAVFEFKALATGDFLIVDHALFRVPKGAG
GLLHVK

Ligand information

• Ligand ID: CU
• InChI: InChI=1S/Cu/q+2
• InChIKey: JPVYNHNXODAKFH-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Cu+2]
  CACTVS 3.341: [Cu++]
• Formula: Cu
• Name: COPPER (II) ION
• DrugBank: DB14552
• PDB chain: 5zl1 Chain B Residue 401

Receptor-Ligand Complex Structure

Structure summary

• PDB: 5zl1 Hexameric structure of copper-containing nitrite reductase of an anammox organism KSU-1
• Resolution: 3.2 Å
• Binding residue (original residue number in PDB): H111 H157 M162
• Binding residue (residue number reindexed from 1): H91 H137 M142
• Annotation score: 1

Enzymatic activity

• Catalytic site (original residue number in PDB): H111 D114 H116 H147 C148 H157 M162 H261 E283 T284 H310
• Catalytic site (residue number reindexed from 1): H91 D94 H96 H127 C128 H137 M142 H241 E263 T264 H290
• Enzyme Commision number: 1.7.2.1: nitrite reductase (NO-forming).

Gene Ontology

Molecular Function

• GO:0005507 copper ion binding
• GO:0016491 oxidoreductase activity
• GO:0046872 metal ion binding
• GO:0050421 nitrite reductase (NO-forming) activity

External links

• PDB: RCSB:5zl1, PDBe:5zl1, PDBj:5zl1
• PDBsum: 5zl1
• UniProt: I3IR93