Structure of PDB 5zi6 Chain B Binding Site BS01

Receptor Information
>5zi6 Chain B (length=55) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KHDCVICFENEVIAALVPCGHNLFCMECANKICEKRTPSCPVCQTAVTQA
IQIHS
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain5zi6 Chain B Residue 701 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5zi6 Structural and functional characterization of hMEX-3C Ring finger domain as an E3 ubiquitin ligase
Resolution2.2 Å
Binding residue
(original residue number in PDB)		C608 C611 C632
Binding residue
(residue number reindexed from 1)		C4 C7 C28
Annotation score4
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:5zi6, PDBe:5zi6, PDBj:5zi6
PDBsum5zi6
PubMed30095198
UniProtQ5U5Q3|MEX3C_HUMAN RNA-binding E3 ubiquitin-protein ligase MEX3C (Gene Name=MEX3C)

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