Structure of PDB 5zhw Chain B Binding Site BS01

Receptor Information
>5zhw Chain B (length=181) Species: 226185 (Enterococcus faecalis V583) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EWSLILVNRQNPIPAQYDVELEQLSNGERIDIRISPYLQDLFDAARADGV
YPIVASGYRTTEKQQEIMDEKVAEYKAKGYTSAQAKAEAETWVAVPGTSE
HQLGLAVDINADGIHSTGNEVYRWLDENSYRFGFIRRYPPDKTEITGVSN
EPWHYRYVGIEAATKIYHQGLCLEEYLNTEK
Ligand information
Ligand IDCU
InChIInChI=1S/Cu/q+2
InChIKeyJPVYNHNXODAKFH-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Cu+2]
CACTVS 3.341[Cu++]
FormulaCu
NameCOPPER (II) ION
ChEMBL
DrugBankDB14552
ZINC
PDB chain5zhw Chain B Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5zhw Structural basis for the substrate recognition of peptidoglycan pentapeptides by Enterococcus faecalis VanYB.
Resolution2.18 Å
Binding residue
(original residue number in PDB)		H188 D195 H241
Binding residue
(residue number reindexed from 1)		H101 D108 H154
Annotation score3
Enzymatic activity
Enzyme Commision number 3.4.17.-
Gene Ontology
Molecular Function
GO:0008233 peptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:5zhw, PDBe:5zhw, PDBj:5zhw
PDBsum5zhw
PubMed30016658
UniProtQ47746|VANY_ENTFA D-alanyl-D-alanine carboxypeptidase (Gene Name=vanYB)

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