Structure of PDB 5zcw Chain B Binding Site BS01

Receptor Information
>5zcw Chain B (length=429) Species: 2209 (Methanosarcina mazei) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MNPKRIRALKSGKQGDGPVVYWMSRDQRAEDNWALLFSRAIAKEANVPVV
VVFCLTDEFLEAGIRQYEFMLKGLQELEVSLSRKKIPSFFLRGDPGEKIS
RFVKDYNAGTLVTDFSPLRIKNQWIEKVISGISIPFFEVDAHNVVPCWEA
SQKHEYAAHTFRPKLYALLPEFLEEFPELEPNSVTPEKDPLFEPWHFEPG
EKAAKKVMESFIADRLDSYGALRNDPTKNMLSNLSPYLHFGQISSQRVVL
EVEKAESNPGSKKAFLDEILIWKEISDNFCYYNPGYDGFESFPSWAKESL
NAHRNDVRSHIYTLEEFEAGKTHDPLWNASQMELLSTGKMHGYTRMYWAK
KILEWSESPEKALEIAICLNDRYELDGRDPNGYAGIAWSIGGVHDRAWGE
REVTGKIRYMSYEGCKRKFDVKLYIEKYS
Ligand information
Receptor-Ligand Complex Structure
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PDB5zcw Twist and turn: a revised structural view on the unpaired bubble of class II CPD photolyase in complex with damaged DNA.
Resolution2.7 Å
Binding residue
(original residue number in PDB)
R256 E301 W305 Y376 M379 W421 W431 R441 Y442 M443 S444 R450
Binding residue
(residue number reindexed from 1)
R223 E268 W272 Y343 M346 W388 W398 R408 Y409 M410 S411 R417
Enzymatic activity
Enzyme Commision number 4.1.99.3: deoxyribodipyrimidine photo-lyase.
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003677 DNA binding
GO:0003904 deoxyribodipyrimidine photo-lyase activity
GO:0016829 lyase activity
Biological Process
GO:0000719 photoreactive repair
GO:0006281 DNA repair

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Molecular Function

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Biological Process
External links
PDB RCSB:5zcw, PDBe:5zcw, PDBj:5zcw
PDBsum5zcw
PubMed30224964
UniProtQ8PYK9

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