Structure of PDB 5zch Chain B Binding Site BS01

Receptor Information
>5zch Chain B (length=299) Species: 39947 (Oryza sativa Japonica Group) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PVWGCASTRGRSAEMEDASAAVPRFADVPVRLLASRRDLDALGLDADALR
LPAHLFGVFDGHGGAEVANYCRERIHVVLSAALARLGKNLGEMGEVDMKE
HWDDVFTKCFQRVDDEVSGRVTRVVGEVRSEPVTAENVGSTAVVALVCSS
HVVVANCGDSRIVLCRGEPVALSIDHKPDRKDERARIEAQGGKVIQWNGY
RVSGWLAMSRSIGDRYLKPFVIPKPEVMVVPRAKDDDCLILASDGLWDVV
SNEEACKVARRQILLSTDPAAQAAADYLMRLALKKGSEDNITVIVVDLK
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain5zch Chain B Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5zch Comprehensive survey of the VxG Phi L motif of PP2Cs from Oryza sativa reveals the critical role of the fourth position in regulation of ABA responsiveness.
Resolution2.474 Å
Binding residue
(original residue number in PDB)		D118 G119
Binding residue
(residue number reindexed from 1)		D60 G61
Annotation score1
Enzymatic activity
Enzyme Commision number 3.1.3.16: protein-serine/threonine phosphatase.
Gene Ontology
Molecular Function
GO:0004722 protein serine/threonine phosphatase activity
GO:0043169 cation binding
Biological Process
GO:0006470 protein dephosphorylation

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Molecular Function
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Biological Process
External links
PDB RCSB:5zch, PDBe:5zch, PDBj:5zch
PDBsum5zch
PubMed31541388
UniProtQ6L5H6|P2C50_ORYSJ Protein phosphatase 2C 50 (Gene Name=PP2C50)

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