Structure of PDB 5ywr Chain B Binding Site BS01

Receptor Information
>5ywr Chain B (length=87) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SGFKCPICSKSVASDEMEMHFIMCLSKPRLSYNDDVLTKDAGECVICLEE
LLQGDTIARLPCLCIYHKSCIDSWFEVNRSCPEHPAD
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain5ywr Chain B Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5ywr Structural insights into the nanomolar affinity of RING E3 ligase ZNRF1 for Ube2N and its functional implications.
Resolution1.47 Å
Binding residue
(original residue number in PDB)		C184 C187 H207 C210
Binding residue
(residue number reindexed from 1)		C44 C47 H67 C70
Annotation score4
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
External links
PDB RCSB:5ywr, PDBe:5ywr, PDBj:5ywr
PDBsum5ywr
PubMed29626159
UniProtQ8ND25|ZNRF1_HUMAN E3 ubiquitin-protein ligase ZNRF1 (Gene Name=ZNRF1)

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