Structure of PDB 5y3m Chain B Binding Site BS01

Receptor Information
>5y3m Chain B (length=732) Species: 9913 (Bos taurus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LPAFLPCELQPHGQVDCNWLFLKSVPHFSAGAPRANVTSLSLISNRIHHL
HDSDFVHLSNLRVLNLKWNCPPAGLSPMHFPCRMTIEPNTFLAVPTLEEL
NLSYNGITTVPALPSSLVSLSLSHTSILVLGPTHFTGLHALRFLYMDGNC
YYMNPCPRALEVAPGALLGLGNLTHLSLKYNNLTEVPRRLPPSLDTLLLS
YNHIVTLAPEDLANLTALRVLDVGGNCRRCDHARNPCRECPKNFPKLHPD
TFSHLSRLEGLVLKDSSLYKLEKDWFRGLGRLQVLDLSENFLYDYITKTT
IFNDLTQLRRLNLSFNYHKKVSFAHLHLASSFGSLVSLEKLDMHGIFFRS
LTNITLQSLTRLPKLQSLHLQLNFINQAQLSIFGAFPSLLFVDLSDNRIS
SCNLNFTLDLSRNNLVTIQQEMFTRLSRLQCLRLSHNSISQAVNGSQFVP
LTSLRVLDLSHNKLDLYHGRSFTELPQLEALDLSYNSQPFSMQGVGHNLS
FVAQLPSLRYLSLAHNGIHSRVSQKLSSASLRALDFSGNSLSQMWAEGDL
YLCFFKGLRNLVQLDLSENHLHTLLPRHLDNLPKSLRQLRLRDNNLAFFN
WSSLTVLPRLEALDLAGNQLKALSNGSLPPGIRLQKLDVSSNSIGFVIPG
FFVRATRLIELNLSANALKTVDPSWFGSLAGTLKILDVSANPLHCAAFVD
FLLERQEAVPGLSRRVTCGSPGQLQGRSIFTQ
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5y3m Toll-like Receptor 9 Contains Two DNA Binding Sites that Function Cooperatively to Promote Receptor Dimerization and Activation
Resolution2.5 Å
Binding residue
(original residue number in PDB)		D532 Y534 G563 H564 R588 V589
Binding residue
(residue number reindexed from 1)		D465 Y467 G496 H497 R521 V522
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004888 transmembrane signaling receptor activity
Biological Process
GO:0002224 toll-like receptor signaling pathway
GO:0006955 immune response
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5y3m, PDBe:5y3m, PDBj:5y3m
PDBsum5y3m
PubMed29625894
UniProtQ5I2M5|TLR9_BOVIN Toll-like receptor 9 (Gene Name=TLR9)

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