Structure of PDB 5xw8 Chain B Binding Site BS01

Receptor Information
>5xw8 Chain B (length=98) Species: 9823 (Sus scrofa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SSGSSYPSLLQCLKAPVLSDSSCKSSYPGQITGNMICVGFLEGGKDSCQG
DSGGPVVCNGQLQGIVSWGYGCAQKNKPGVYTKVCNYVNWIQQTIAAN
Ligand information
Receptor-Ligand Complex Structure
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PDB5xw8 Tripeptides derived from reactive centre loop of potato type II protease inhibitors preferentially inhibit midgut proteases of Helicoverpa armigera.
Resolution2.002 Å
Binding residue
(original residue number in PDB)		D179 S180 C181 Q182 G183 S185 W201 G202
Binding residue
(residue number reindexed from 1)		D46 S47 C48 Q49 G50 S52 W68 G69
Enzymatic activity
Catalytic site (original residue number in PDB) Q182 G183 D184 S185 G186
Catalytic site (residue number reindexed from 1) Q49 G50 D51 S52 G53
Enzyme Commision number 3.4.21.4: trypsin.
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:5xw8, PDBe:5xw8, PDBj:5xw8
PDBsum5xw8
PubMed29486250
UniProtP00761|TRYP_PIG Trypsin

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