Structure of PDB 5xfp Chain B Binding Site BS01
Receptor Information
>5xfp Chain B (length=305) Species:
9606
(Homo sapiens) [
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RLWEGQDVLARWTDGLLYLGTIKKVDSAREVCLVQFEDDSQFLVLWKDIS
PAALPGEELLCCVCRSETVVPGNRLVSCEKCRHAYHQDCHVPRAPAPSWV
CRQCVFAIATKRGGALKKGPYARAMLGMKLSLPYGLKGLDWDAGHLSNRQ
QSYCYCGGPGEWNLKMLQCRSCLQWFHEACTQCLSKPLLYGDRFYEFECC
VCRGGPEKVRRLQLRWVDVAHLVLYHLSVCCKKKYFDFDREILPFTSENW
DSLLLGELSDTPKGERSSRLLSALNSHKDRFISGREIKKRKCLFGLHARM
PPPVE
Ligand information
>5xfp Chain C (length=13) [
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gggcggccgccct
Receptor-Ligand Complex Structure
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PDB
5xfp
Polycomb-like proteins link the PRC2 complex to CpG islands
Resolution
2.3 Å
Binding residue
(original residue number in PDB)
K323 K324 R325 K326
Binding residue
(residue number reindexed from 1)
K288 K289 R290 K291
Binding affinity
PDBbind-CN
: Kd=1.2uM
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5xfp
,
PDBe:5xfp
,
PDBj:5xfp
PDBsum
5xfp
PubMed
28869966
UniProt
O43189
|PHF1_HUMAN PHD finger protein 1 (Gene Name=PHF1)
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