Structure of PDB 5xch Chain B Binding Site BS01

Receptor Information
>5xch Chain B (length=180) Species: 5759 (Entamoeba histolytica) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MLVLVIGDFHVPHRSAAIPQVFLDRLNTGRIQTVLCTGNLCGKETYDILR
TLAREVHVVKGDFDEMQGLNETEVIKIGNFKIGLMHGHQVIPWGDREALA
IYQRQLDVDILITGHTHKLETKEVGGKYFLNPGSATGAYSPLVDNPVPSF
MLLEINDSELTIYEYTLVDGSVKCERVDFN
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain5xch Chain B Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5xch Structural and thermodynamic characterization of metal binding in Vps29 from Entamoeba histolytica: implication in retromer function.
Resolution2.85 Å
Binding residue
(original residue number in PDB)		D62 H86 H115
Binding residue
(residue number reindexed from 1)		D62 H86 H115
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0046872 metal ion binding
Biological Process
GO:0006886 intracellular protein transport
GO:0015031 protein transport
GO:0042147 retrograde transport, endosome to Golgi
Cellular Component
GO:0005768 endosome
GO:0005829 cytosol
GO:0030904 retromer complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5xch, PDBe:5xch, PDBj:5xch
PDBsum5xch
PubMed28898487
UniProtQ9BI08

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