Structure of PDB 5x2m Chain B Binding Site BS01

Receptor Information
>5x2m Chain B (length=452) Species: 8090 (Oryzias latipes) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PNWFNNISTDLFSMPGDIKLGGLFPIKEQSVSCDSLNKDGLGRALVMKYA
VEEINANSQLLPGVKLGYKIYNTCRHSAVIVRPALSFLTEKSNGTLSVEC
NYTDYETDMVAVIGPQSSEMVTVIGKLLGFFLMPQISFGATSDKFSDSLV
YPSFFRTVPSDIRQVDAMVQLIKKFNWNWVAVVGSEEEYGQQGVQQFSKK
AEDMGVCVAYQGLIPIYDDPKPAIQTIINNIQTTEVKVVVVFSLVSPAVS
FFEEVIKKNLTGVWIASSSWAISDKVYSLPNIDSIGTVIGFIDETETLEL
LSPFTEVLFKKIHEASPTYNPCPECWSLSPANVSLVKEESVQRTAFSVYA
AVYTVAHALHKLLECNSAACKWSSSTRLYPWKLLEVLKEFSVNISNTSLK
FDQNGNPNIGYSVIQRIWENQSLSSVGSYRSANLSINETLFKWYTNNSEK
PE
Ligand information
Ligand IDGLN
InChIInChI=1S/C5H10N2O3/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H2,7,8)(H,9,10)/t3-/m0/s1
InChIKeyZDXPYRJPNDTMRX-VKHMYHEASA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C(CC(=O)N)C(C(=O)O)N
OpenEye OEToolkits 1.5.0C(CC(=O)N)[C@@H](C(=O)O)N
ACDLabs 10.04O=C(N)CCC(N)C(=O)O
CACTVS 3.341N[CH](CCC(N)=O)C(O)=O
CACTVS 3.341N[C@@H](CCC(N)=O)C(O)=O
FormulaC5 H10 N2 O3
NameGLUTAMINE
ChEMBLCHEMBL930
DrugBankDB00130
ZINCZINC000001532526
PDB chain5x2m Chain B Residue 951 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5x2m Structural basis for perception of diverse chemical substances by T1r taste receptors
Resolution2.206 Å
Binding residue
(original residue number in PDB)		R107 Q148 S149 S150 G171 A172 T173 Y221
Binding residue
(residue number reindexed from 1)		R75 Q116 S117 S118 G139 A140 T141 Y189
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004930 G protein-coupled receptor activity
Biological Process
GO:0007186 G protein-coupled receptor signaling pathway
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5x2m, PDBe:5x2m, PDBj:5x2m
PDBsum5x2m
PubMed28534491
UniProtA0A173M094

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