Structure of PDB 5wtb Chain B Binding Site BS01
Receptor Information
>5wtb Chain B (length=319) Species:
158878
(Staphylococcus aureus subsp. aureus Mu50) [
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NNVNDLITVTKQTIKVGDNVAAAHDGKDIEYDTEFTIDNKVKKGDTMTIN
YDKNVIPSDLTDKNDPIDITDPSGEVIAKGTFDKATKQITYTFTDYVDKY
EDIKARLTLYSYIDKQAVPNETSLNLTFATAGKETSQNVSVDYQDPMVHG
DSNIQSIFTKLDENKQTIEQQIYVNPLKKTATNTKVDIAGSQVDDYGNIK
LGNGSTIIDQNTEMKVYKVNPNQQLPQSNRIYDFSQYEDVTSQFDNKKSF
SNNVATLDFGDINSAYIIKVVSKYTPTSDGELDIAQGTSMRTTDYNYAGY
SNFIVTSNDTGGGDGTVKP
Ligand information
>5wtb Chain F (length=14) Species:
9606
(Homo sapiens) [
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RLSSRSHTLRTTCW
Receptor-Ligand Complex Structure
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PDB
5wtb
Staphylococcus aureus SdrE captures complement factor H's C-terminus via a novel 'close, dock, lock and latch' mechanism for complement evasion
Resolution
3.3 Å
Binding residue
(original residue number in PDB)
H299 D300 G301 P332 S333 D334 L335 T336 N339 D340 Y387 Q419 F433 Y579 S580 N581 F582 I583 V584 T585 S586 N587
Binding residue
(residue number reindexed from 1)
H24 D25 G26 P57 S58 D59 L60 T61 N64 D65 Y112 Q144 F158 Y300 S301 N302 F303 I304 V305 T306 S307 N308
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Biological Process
GO:0007155
cell adhesion
Cellular Component
GO:0005618
cell wall
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Biological Process
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Cellular Component
External links
PDB
RCSB:5wtb
,
PDBe:5wtb
,
PDBj:5wtb
PDBsum
5wtb
PubMed
28258151
UniProt
Q932F7
|SDRE_STAAM Serine-aspartate repeat-containing protein E (Gene Name=sdrE)
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