Structure of PDB 5wai Chain B Binding Site BS01
Receptor Information
>5wai Chain B (length=300) Species:
9606
(Homo sapiens) [
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VQADHELFLQAFEKPTQIYRFLRTRNLIAPIFLHRTLTYMSHRNSRTNIK
RKTFKVDDMLSKVEKMKGEQESAHLQLTFTGFFHKVTLEVLLVKVCHKKR
KDVSCPIRQVPTGKQVPLNPDLNQTKPSLAVSSNEFEPSNSHMVKSYSLL
FRFVAQMTVFDKNRRLQLLDGEYEVAMQEMQGPTLQFTLRWTGRQKLRIF
YQFLYNNNTRQQTEARDDLHCPWCTLNCRKLYSLLKHLKLCHSRFIFNYV
YHPKGARIDVSINECYDFSRNGPVKRTPITHILVCRPKRTKASMSEFLEW
Ligand information
>5wai Chain D (length=15) Species:
452646
(Neogale vison) [
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RKPKTEDFLTFLCLR
Receptor-Ligand Complex Structure
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PDB
5wai
Unique Structural Platforms of Suz12 Dictate Distinct Classes of PRC2 for Chromatin Binding.
Resolution
2.9 Å
Binding residue
(original residue number in PDB)
E84 L87 E91 T94 Q95 R98 Y430 F432 Q440 Q441 T442 E443 A444 R445 P451 W452
Binding residue
(residue number reindexed from 1)
E6 L9 E13 T16 Q17 R20 Y201 F203 Q211 Q212 T213 E214 A215 R216 P222 W223
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5wai
,
PDBe:5wai
,
PDBj:5wai
PDBsum
5wai
PubMed
29499137
UniProt
Q15022
|SUZ12_HUMAN Polycomb protein SUZ12 (Gene Name=SUZ12)
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