Structure of PDB 5w0v Chain B Binding Site BS01

Receptor Information
>5w0v Chain B (length=1003) Species: 28985 (Kluyveromyces lactis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LAGVEARKQVSKHWGSLDAATQTSVKQSLLNSAFNEGKDAVRHANARVIA
SIGSEELDEKKWPELIPNLLQAACDSNPKIRETAIFIILSLLESFNANLA
LHIDDFLNLFAQTINDSASLETRSLSAQALSYVSSLIEEEGEINPQYAAK
FASLIPSVVQVLDATIREGDTTNTKLIFNCLNDFLLLDSQLTGNTIADLV
KLALQIAVNSDVDEDIRVFAVQFVTSALVYRKSKINQAKLGPEITLAALK
VASEEIDVEDELTNEEENTPALTALRLISNASGELSPSQVGVPIIEHLPT
MLSSSNPFERRSILLAISVLVTGSPDYTLSQFDKIIPATVTGLKDSEAVV
QLAALKCIVQLSTNLQDEVARYHEQYLPLVIDIIDSAKHVVIYKYATLAL
DGLLEFIAHNDIIKYLDPLMNKLFQMLETQQSPKLRAAIVSAIGSCAFAA
GSGFVPYFKTSVQYLQQFIQNVSQIEGLSEDDIELKALTFENISTMGRAV
KSAAFAEYAEPLVNAAYEAIKTDSARLRESGYAFIANMAKVYGKDFAPFL
QTIIPEIFKTLEQEEYTVNTGIAYEKEVAAAALSELAIASKEHFLEYVEP
SLKVLAEQVNESYGLKETALHSMWAIVKAVLLTANLKEGEYPKGVPSGSY
VDASALAVIQTVREVSLNNVIEEVETSMVISVFQDLSEMLRLFGPIIIMD
NGDSTHLDQLCREALSVLKGEHACQTIEDLDASETEATLLDVALDIYVAL
STNLVGGFAQVFTTAKPVILQLCQSKSKNKRSFAVGALSEIALGMRDENP
FIQELLEALIISLTNDKSLEVRCNASYGVGLLIEYSSFDVSAIYSPVLKS
LYEILSVADEKNLDEATKEIVDRTFSNVCGCVARMILKHQNLVPLEHTIP
ALLSHLPFNTAFEEYDPIFKLFLKLFQEQNSTIINEAPKVIAIFATVFEK
ESERIELETNSTLGREEKRKQFQSEEIKQQVIELLKHLNQQFVAQNPVLA
QVI
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5w0v Structure-based nuclear import mechanism of histones H3 and H4 mediated by Kap123.
Resolution2.821 Å
Binding residue
(original residue number in PDB)		E469 F470 S505 S509 F512 E593 N601 Y664
Binding residue
(residue number reindexed from 1)		E405 F406 S441 S445 F448 E529 N537 Y574
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0008139 nuclear localization sequence binding
GO:0031267 small GTPase binding
GO:0061608 nuclear import signal receptor activity
Biological Process
GO:0006606 protein import into nucleus
GO:0006886 intracellular protein transport
GO:0051170 import into nucleus
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5w0v, PDBe:5w0v, PDBj:5w0v
PDBsum5w0v
PubMed29035199
UniProtQ6CMF0

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