Structure of PDB 5w0m Chain B Binding Site BS01

Receptor Information
>5w0m Chain B (length=350) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EPLPPLTPKFLNILDQVCIQCYKDFSPTIIEDQAREHIRQNLESFIRQDF
PGTKLSLFGSSKNGFGFKQSDLAVCMTINGLETAEGLDCVRTIEELARVL
RKHSGLRNILPITTAKVPIVKFFHLRSGLEVDISLYNTLALHNTRLLSAY
SAIDPRVKYLCYTMKVFTKMCDIGDASRGSLSSYAYTLMVLYFLQQRNPP
VIPVLQEIYKGKPEIFVDGWNIYFFDQIDELPTYWSECGKNTESVGQLWL
GLLRFYTEEFDFKEHVISIRRKSLLTTFKKQWTSKYIVIEDPFDLNHNLG
AGLSRKMTNFIMKAFINGRRVFGIPVSKMEYFFDPDVLTEGELAPNDRCC
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5w0m Multi-domain utilization by TUT4 and TUT7 in control of let-7 biogenesis.
Resolution2.298 Å
Binding residue
(original residue number in PDB)		F1045 G1046 T1101 A1102 K1103 V1104 N1124 N1130 A1163 S1164 L1288 A1290
Binding residue
(residue number reindexed from 1)		F58 G59 T114 A115 K116 V117 N137 N143 A176 S177 L299 A301
Enzymatic activity
Enzyme Commision number 2.7.7.52: RNA uridylyltransferase.
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0008270 zinc ion binding

View graph for
Molecular Function
External links
PDB RCSB:5w0m, PDBe:5w0m, PDBj:5w0m
PDBsum5w0m
PubMed28671666
UniProtQ5VYS8|TUT7_HUMAN Terminal uridylyltransferase 7 (Gene Name=TUT7)

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