Structure of PDB 5vzu Chain B Binding Site BS01
Receptor Information
>5vzu Chain B (length=418) Species:
9606
(Homo sapiens) [
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SGRSLLELPPELLVEIFASLPGTDLPSLAQVCTKFRRILHTDTIWRRRCR
EEYGVCENLRKLEITGVSCRDVYAKLLHRYRHILGLWQPDIGPYGGLLNV
VVDGLFIIGWMYLPPHDPHVDDPMRFKPLFRIHLMERKAATVECMYGHKG
PHHGHIQIVKKDEFSTKCNQTDHHRMSGGRQEEFRTWLREEWGRTLEDIF
HEHMQELILMKFIYTSQYDNCLTYRRIYLPPSRPDDLIKPGLFKGTYGSH
GLEIVMLSFHGRRARGTKITGDPNIPAGQQTVEIDLRHRIQLPDLENQRN
FNELSRIVLEVRERVRQEQQEGQPFVLPVGVSSRNEDYPRTCRMCFYGTG
LIAGHGFTSPERTPGVFILFDEDRFGFVWLELKSFSLYSRVQATFRNADA
PSPQAFDEMLKNIQSLTS
Ligand information
>5vzu Chain E (length=9) Species:
9606
(Homo sapiens) [
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PTDVRDVDI
Receptor-Ligand Complex Structure
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PDB
5vzu
Structural basis of the phosphorylation-independent recognition of cyclin D1 by the SCFFBXO31 ubiquitin ligase.
Resolution
2.7 Å
Binding residue
(original residue number in PDB)
H265 Y309 H312 K330 D334 N336 I337 S453 I473 A474 W500 L503
Binding residue
(residue number reindexed from 1)
H203 Y247 H250 K268 D272 N274 I275 S332 I352 A353 W379 L382
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5vzu
,
PDBe:5vzu
,
PDBj:5vzu
PDBsum
5vzu
PubMed
29279382
UniProt
Q5XUX0
|FBX31_HUMAN F-box only protein 31 (Gene Name=FBXO31)
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