Structure of PDB 5vs5 Chain B Binding Site BS01

Receptor Information
>5vs5 Chain B (length=296) Species: 3702 (Arabidopsis thaliana) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
CIPLWGTVSIQGNRSEMEDAFAVSPHFLKLPIKMHLTGHFFGVYDGHGGH
KVADYCRDRLHFALAEEIERIKRQVQWDKVFTSCFLTVDGEIEGKIGRAV
VSSDKVLEAVASETVGSTAVVALVCSSHIVVSNCGDSRAVLFRGKEAMPL
SVDHKPDREDEYARIENAGGKVIQWQGARVFGVLAMSRSIGDRYLKPYVI
PEPEVTFMPRSREDECLILASDGLWDVMNNQEVCEIARRRILMWHKKNGA
PPLAERGKGIDPACQAAADYLSMLALQKGSKDNISIIVIDLKAQRK
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain5vs5 Chain B Residue 601 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5vs5 Combining chemical and genetic approaches to increase drought resistance in plants.
Resolution2.8 Å
Binding residue
(original residue number in PDB)		D243 D346 S347 S431 D432
Binding residue
(residue number reindexed from 1)		D45 D136 S137 S221 D222
Annotation score1
Enzymatic activity
Enzyme Commision number 3.1.3.16: protein-serine/threonine phosphatase.
Gene Ontology
Molecular Function
GO:0004722 protein serine/threonine phosphatase activity
GO:0043169 cation binding
Biological Process
GO:0006470 protein dephosphorylation

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Molecular Function
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Biological Process
External links
PDB RCSB:5vs5, PDBe:5vs5, PDBj:5vs5
PDBsum5vs5
PubMed29084945
UniProtQ9CAJ0|P2C16_ARATH Protein phosphatase 2C 16 (Gene Name=HAB1)

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