Structure of PDB 5vng Chain B Binding Site BS01

Receptor Information
>5vng Chain B (length=728) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GLRVVNLLQERNMLPSTPLKPPVPNLHEDIQKLNCNPELFRCTLTSIPQT
QALLNKAKLPLGLLLHPFKDLVQLPVVTSSTIVRCRSCRTYINPFVSFLD
QRRWKCNLCYRVNDVPEEEPHRRPEVQNATIEFMAPSEYMLRPPQPPVYL
FVFDVSHNAVETGYLNSVCQSLLDNLDLLPGNTRTKIGFITFDSTIHFYG
LQESLSQPQMLIVSDIEDVFIPMPENLLVNLNESKELVQDLLKTLPQMFT
KTLETQSALGPALQAAFKLMSPTGGRMSVFQTQLPTLGVGALKPREEPNH
RSSAKMTPSTDFYKKLALDCSGQQVAVDLFLLSGQYSDLASLGCISRYSA
GSVYYYPSYHHQHNPVQVQKLQKELQRYLTRKIGFEAVMRIRCTKGLSIH
TFHGNFFVRSTDLLSLPNVNPDAGYAVQMSVEESLTDTQLVSFQSALLYT
SSKGERRIRVHTLCLPVVSTLNDVFLGADVQAISGLLANMAVDRSMTASL
SDARDALVNAVIDSLSAYRSSVPGLMVPFSLRLFPLFVLALLKQKSFQTG
TNARLDERIFAMCQVKNQPLVYLMLTTHPSLYRVDNLSDEGALNISDRTI
PQPPILQLSVEKLSRDGAFLMDAGSVLMLWVGKNCTQNFLSQVLGVQNYA
SIPQPMTDLPELDTPESARIIAFISWLREQRPFFPILYVIADESPMKANF
LQNMIEDRTESALSYYEFLLHIQQQVNK
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5vng ER retention is imposed by COPII protein sorting and attenuated by 4-phenylbutyrate.
Resolution2.6 Å
Binding residue
(original residue number in PDB)		R430 Y437 Y496 R750 R752 L773 A806
Binding residue
(residue number reindexed from 1)		R84 Y91 Y139 R390 R392 L413 A446
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding
Biological Process
GO:0006886 intracellular protein transport
GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport
Cellular Component
GO:0030127 COPII vesicle coat

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5vng, PDBe:5vng, PDBj:5vng
PDBsum5vng
PubMed28594326
UniProtO95486|SC24A_HUMAN Protein transport protein Sec24A (Gene Name=SEC24A)

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