Structure of PDB 5vne Chain B Binding Site BS01

Receptor Information
>5vne Chain B (length=729) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EGLRVVNLLQERNMLPSTPLKPPVPNLHEDIQKLNCNPELFRCTLTSIPQ
TQALLNKAKLPLGLLLHPFKDLVQLPVVTSSTIVRCRSCRTYINPFVSFL
DQRRWKCNLCYRVNDVPEEEPHRRPEVQNATIEFMAPSEYMLRPPQPPVY
LFVFDVSHNAVETGYLNSVCQSLLDNLDLLPGNTRTKIGFITFDSTIHFY
GLQESLSQPQMLIVSDIEDVFIPMPENLLVNLNESKELVQDLLKTLPQMF
TKTLETQSALGPALQAAFKLMSPTGGRMSVFQTQLPTLGVGALKPREEPN
HRSSAKMTPSTDFYKKLALDCSGQQVAVDLFLLSGQYSDLASLGCISRYS
AGSVYYYPSYHHQHNPVQVQKLQKELQRYLTRKIGFEAVMRIRCTKGLSI
HTFHGNFFVRSTDLLSLPNVNPDAGYAVQMSVEESLTDTQLVSFQSALLY
TSSKGERRIRVHTLCLPVVSTLNDVFLGADVQAISGLLANMAVDRSMTAS
LSDARDALVNAVIDSLSAYRSSVPGLMVPFSLRLFPLFVLALLKQKSFQT
GTNARLDERIFAMCQVKNQPLVYLMLTTHPSLYRVDNLSDEGALNISDRT
IPQPPILQLSVEKLSRDGAFLMDAGSVLMLWVGKNCTQNFLSQVLGVQNY
ASIPQPMTDLPELDTPESARIIAFISWLREQRPFFPILYVIADESPMKAN
FLQNMIEDRTESALSYYEFLLHIQQQVNK
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5vne ER retention is imposed by COPII protein sorting and attenuated by 4-phenylbutyrate.
Resolution2.698 Å
Binding residue
(original residue number in PDB)		R430 E495 Y496 R752 L773
Binding residue
(residue number reindexed from 1)		R85 E139 Y140 R393 L414
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding
Biological Process
GO:0006886 intracellular protein transport
GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport
Cellular Component
GO:0030127 COPII vesicle coat

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5vne, PDBe:5vne, PDBj:5vne
PDBsum5vne
PubMed28594326
UniProtO95486|SC24A_HUMAN Protein transport protein Sec24A (Gene Name=SEC24A)

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