Structure of PDB 5vf0 Chain B Binding Site BS01

Receptor Information
>5vf0 Chain B (length=43) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QVTKVDCPVCGVNIPESHINKHLDSCLSREEKKESLRSSVHKR
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain5vf0 Chain B Residue 300 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5vf0 Mechanisms of Ubiquitin-Nucleosome Recognition and Regulation of 53BP1 Chromatin Recruitment by RNF168/169 and RAD18.
ResolutionN/A
Binding residue
(original residue number in PDB)		C204 C207 H219 C223
Binding residue
(residue number reindexed from 1)		C7 C10 H22 C26
Annotation score4
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003697 single-stranded DNA binding
GO:0061630 ubiquitin protein ligase activity
Biological Process
GO:0006281 DNA repair
GO:0006301 postreplication repair
GO:0006513 protein monoubiquitination

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Molecular Function
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Biological Process
External links
PDB RCSB:5vf0, PDBe:5vf0, PDBj:5vf0
PDBsum5vf0
PubMed28506460
UniProtQ9NS91|RAD18_HUMAN E3 ubiquitin-protein ligase RAD18 (Gene Name=RAD18)

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