Structure of PDB 5ve9 Chain B Binding Site BS01

Receptor Information
>5ve9 Chain B (length=91) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GPGGHMANFDFDVWRKKYMRWMNHKKSRVMDFFRRIDKDQDGKITRQEFI
DGILASKFPTTKLEMTAVADIFDRDGDGYIDYYEFVAALHP
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain5ve9 Chain B Residue 7201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5ve9 Structure of the ACF7 EF-Hand-GAR Module and Delineation of Microtubule Binding Determinants.
Resolution2.795 Å
Binding residue
(original residue number in PDB)		D7054 D7056 D7058 K7060
Binding residue
(residue number reindexed from 1)		D37 D39 D41 K43
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
Biological Process
GO:0045104 intermediate filament cytoskeleton organization

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Molecular Function
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Biological Process
External links
PDB RCSB:5ve9, PDBe:5ve9, PDBj:5ve9
PDBsum5ve9
PubMed28602822
UniProtQ9UPN3|MACF1_HUMAN Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4/5 (Gene Name=MACF1)

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