Structure of PDB 5vbc Chain B Binding Site BS01

Receptor Information
>5vbc Chain B (length=215) Species: 3988 (Ricinus communis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RLLPFVSSEDPAQRLKQMGTLASALTELQMEFSDDLTYSSGMAPRSANQA
RFEEGGMQVLTKEDIETLEQCRAMCKRGDCPPLLVVFDSREGFTVEADGQ
IKDMTFIAEYTGDVDYIRNREHDDCDSMMTLLLAKDPSKSLVICPDKRGN
IARFISGINNHTLDGKKKQNCKCVRYSVNGECRVFLVATRDIAKGERLYY
DYNGYEHEYPTQHFV
Ligand information
>5vbc Chain D (length=13) Species: 3702 (Arabidopsis thaliana) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
AARKSAPATGGVK
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5vbc Molecular basis for the methylation specificity of ATXR5 for histone H3.
Resolution2.1 Å
Binding residue
(original residue number in PDB)		M216 Q217 D262 M263 Y269 S286 M287 M288 T289 K331 C332 R334 T348 Y361 G363 Y364 E365 E367 Y368
Binding residue
(residue number reindexed from 1)		M57 Q58 D103 M104 Y110 S127 M128 M129 T130 K172 C173 R175 T189 Y202 G204 Y205 E206 E208 Y209
Enzymatic activity
Enzyme Commision number 2.1.1.369: [histone H3]-lysine(27) N-methyltransferase.
External links
PDB RCSB:5vbc, PDBe:5vbc, PDBj:5vbc
PDBsum5vbc
PubMed28383693
UniProtB9RU15|ATXR5_RICCO Probable Histone-lysine N-methyltransferase ATXR5 (Gene Name=ATXR5)

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