Structure of PDB 5vay Chain B Binding Site BS01
Receptor Information
>5vay Chain B (length=145) Species:
9606
(Homo sapiens) [
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AGRTGYDNREIVMKYIHYKLSQRGYEWDESEVVHLTLRQAGDDFSRRYRR
DFAEMSSQLHLTPFTARGRFATVVEELFRDGVNWGRIVAFFEFGGVMCVE
SVNREMSPLVDNIALWMTEYLNRHLHTWIQDNGGWDAFVELYGPS
Ligand information
>5vay Chain F (length=21) Species:
9606
(Homo sapiens) [
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DMENLSRRLKVTGDLFDIMSG
Receptor-Ligand Complex Structure
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PDB
5vay
Bcl-2 complex with Beclin 1 pT108 BH3 domain
Resolution
1.804 Å
Binding residue
(original residue number in PDB)
D103 F104 R107 Y108 F112 M115 R129 V133 E136 L137 D140 N143 G145 R146 F153 Y202
Binding residue
(residue number reindexed from 1)
D43 F44 R47 Y48 F52 M55 R69 V73 E76 L77 D80 N83 G85 R86 F93 Y142
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Biological Process
GO:0042981
regulation of apoptotic process
View graph for
Biological Process
External links
PDB
RCSB:5vay
,
PDBe:5vay
,
PDBj:5vay
PDBsum
5vay
PubMed
UniProt
P10415
|BCL2_HUMAN Apoptosis regulator Bcl-2 (Gene Name=BCL2);
Q07817
|B2CL1_HUMAN Bcl-2-like protein 1 (Gene Name=BCL2L1)
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