Structure of PDB 5vax Chain B Binding Site BS01

Receptor Information
>5vax Chain B (length=147) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TGYDNREIVMKYIHYKLSQRGYEWDEGTESEVVHLTLRQAGDDFSRRYRR
DFAEMSSQLHLTPFTARGRFATVVEELFRDGVNWGRIVAFFEFGGVMCVE
SVNREMSPLVDNIALWMTEYLNRHLHTWIQDNGGWDAFVELYGPSMR
Ligand information
>5vax Chain F (length=21) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
TMENLSRRLKVTGDLFDIMSG
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5vax Bcl-2 complex with Beclin 1 pT108 BH3 domain
Resolution2.0 Å
Binding residue
(original residue number in PDB)		A100 F104 R107 Y108 F112 M115 L119 R129 V133 E136 L137 D140 N143 G145 R146 F153 Y202
Binding residue
(residue number reindexed from 1)		A40 F44 R47 Y48 F52 M55 L59 R69 V73 E76 L77 D80 N83 G85 R86 F93 Y142
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0042981 regulation of apoptotic process

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Biological Process
External links
PDB RCSB:5vax, PDBe:5vax, PDBj:5vax
PDBsum5vax
PubMed
UniProtP10415|BCL2_HUMAN Apoptosis regulator Bcl-2 (Gene Name=BCL2)

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