Structure of PDB 5va6 Chain B Binding Site BS01
Receptor Information
>5va6 Chain B (length=215) Species:
3988
(Ricinus communis) [
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RLLPFVSSEDPAQRLKQMGTLASALTELQMEFSDDLTYSSGMAPRSANQA
RFEEGGMQVLTKEDIETLEQCRAMCKRGDCPPLLVVFDSREGFTVEADGQ
IKDMTFIAEYTGDVDYIRNREHDDCDSMMTLLLAKDPSSSLVICPDKRGN
IARFISGINNHTLDAKKKQNCKCVRYSVNGECRVFLVATRDIAKGERLYY
DYNGYEHEYPTQHFV
Ligand information
>5va6 Chain D (length=13) Species:
9606
(Homo sapiens) [
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KAARKSAPATGGV
Receptor-Ligand Complex Structure
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PDB
5va6
Molecular basis for the methylation specificity of ATXR5 for histone H3.
Resolution
2.4 Å
Binding residue
(original residue number in PDB)
M216 Q217 M263 Y269 I276 E280 H281 S286 M287 M288 T289 V301 K331 C332 R334 Y361 G363 Y364 E365 E367 Y368
Binding residue
(residue number reindexed from 1)
M57 Q58 M104 Y110 I117 E121 H122 S127 M128 M129 T130 V142 K172 C173 R175 Y202 G204 Y205 E206 E208 Y209
Enzymatic activity
Enzyme Commision number
2.1.1.369
: [histone H3]-lysine(27) N-methyltransferase.
External links
PDB
RCSB:5va6
,
PDBe:5va6
,
PDBj:5va6
PDBsum
5va6
PubMed
28383693
UniProt
B9RU15
|ATXR5_RICCO Probable Histone-lysine N-methyltransferase ATXR5 (Gene Name=ATXR5)
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