Structure of PDB 5v1s Chain B Binding Site BS01

Receptor Information
>5v1s Chain B (length=427) Species: 1307 (Streptococcus suis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MRTISEDILFRLEKFGGILINKTNFERIELDETEAFFLYLVQNHGIEIAT
SFFKKEIEMGKLERALSLNIYSDNNIEDSLNNPYETLQNARKHVAKLKKH
NILSFPLELVIYPSMYCDLKCGFCFLNAKPAKDWERILRQAKDNGVLSVS
ILGGEPTRYFDIDNLLIACEELKIKTTITTNAQLIKKSTVEILAKSKYIT
PVLSLQTLDSKLNFELMGVRPDRQIKLAKYFNEVGKKCRINAVYTKQSYE
QIIELVDFCIENKIDRFSVANYSEIKKKYDLADLRRLNEYVTDYITQREA
NLNFATEGCHLFTAYPELINNSIEFSEFDEMYYGCRAKYTKMEIMSNGDI
LPCIAFLGVNQTKQNAFEKDLLDVWYDDPLYGGIRSFRTKNSKCLSCGLL
KICEGGCYVNLIKEKSPEYFRDSVCQL
Ligand information
Ligand IDSF4
InChIInChI=1S/4Fe.4S
InChIKeyLJBDFODJNLIPKO-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 2.0.7[S]12[Fe]3[S]4[Fe]1[S]5[Fe]2[S]3[Fe]45
CACTVS 3.385S1[Fe]S[Fe]1.S2[Fe]S[Fe]2
FormulaFe4 S4
NameIRON/SULFUR CLUSTER
ChEMBL
DrugBank
ZINC
PDB chain5v1s Chain B Residue 601 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5v1s Structures of the peptide-modifying radical SAM enzyme SuiB elucidate the basis of substrate recognition.
Resolution2.492 Å
Binding residue
(original residue number in PDB)		C117 K120 C121 C124
Binding residue
(residue number reindexed from 1)		C117 K120 C121 C124
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0046872 metal ion binding
GO:0051536 iron-sulfur cluster binding
GO:0051539 4 iron, 4 sulfur cluster binding

View graph for
Molecular Function
External links
PDB RCSB:5v1s, PDBe:5v1s, PDBj:5v1s
PDBsum5v1s
PubMed28893989
UniProtA0A0Z8EWX1

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