Structure of PDB 5uof Chain B Binding Site BS01

Receptor Information
>5uof Chain B (length=459) Species: 395019 (Burkholderia multivorans ATCC 17616) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MSRLIVVSNRVAIGEDTRPSAGGLAVGVMDALQETGGVWFGWNGEIVGTP
DAAPAIRRDGNVTYATVGLTRRDYDQYYRGFSNATLWPVFHYRGDLARFD
RQEYAGYLRVNAMLAKQLAALLRPDDLIWVHDYHLLPFAHALRELGVKNP
IGFFLHIPFPSPDVLRLVPPHDELVKFMCAYDVTGFQTDADRQAFTDYIE
RRGIGTASEDGMLHAHGRVVKVAAYPIGVYPDAIAQAAVQYGARKPVKML
RDALGGRKLVMSVDRLDYSKGLVERFQAFERMLANAPGWQGRVSLVQIAP
PTDVQTYQRIRETLEGEAGRINGRFSQLDWTPIQYLNRKYERNLLMAFFR
MSQVGYVTPLRDGMNLVAKEYVASQDPADPGVLVLSEFAGAAAELTGALL
VNPYDLSQMADALERALSMPLAERQARHEENLARLRANDLSVWRDTFVAD
LRSVAAAAS
Ligand information
Ligand IDSER
InChIInChI=1S/C3H7NO3/c4-2(1-5)3(6)7/h2,5H,1,4H2,(H,6,7)/t2-/m0/s1
InChIKeyMTCFGRXMJLQNBG-REOHCLBHSA-N
SMILES
SoftwareSMILES
CACTVS 3.341N[CH](CO)C(O)=O
OpenEye OEToolkits 1.5.0C(C(C(=O)O)N)O
CACTVS 3.341N[C@@H](CO)C(O)=O
ACDLabs 10.04O=C(O)C(N)CO
OpenEye OEToolkits 1.5.0C([C@@H](C(=O)O)N)O
FormulaC3 H7 N O3
NameSERINE
ChEMBLCHEMBL11298
DrugBankDB00133
ZINCZINC000000895034
PDB chain5uof Chain B Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5uof Crystal structure of alpha,alpha-trehalose 6-phosphate sythase from Burkholderia multivorans
Resolution1.7 Å
Binding residue
(original residue number in PDB)		F107 P177 P178
Binding residue
(residue number reindexed from 1)		F99 P169 P170
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) H164 D372
Catalytic site (residue number reindexed from 1) H156 D362
Enzyme Commision number 2.4.1.15: alpha,alpha-trehalose-phosphate synthase (UDP-forming).
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0003825 alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity
GO:0016757 glycosyltransferase activity
GO:0016758 hexosyltransferase activity
Biological Process
GO:0005992 trehalose biosynthetic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:5uof, PDBe:5uof, PDBj:5uof
PDBsum5uof
PubMed
UniProtA0A0H3KGN3

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