Structure of PDB 5uk4 Chain B Binding Site BS01

Receptor Information
>5uk4 Chain B (length=412) Species: 11285 (Vesicular stomatitis Indiana virus strain San Juan) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SVTVKRIIDNTVIVPKLPANEDPVEYPADYFRKSKEIPLYINTTKSLSDL
RGYVYQGLKSVSIIHVNSYLYGALKDIRGKLDKDWSSFGINIGKAGDTIG
IFDLVSLKALDSDASRTSADDKWLPLYLLGLYRVGRTQMPEYRKKLMDGL
TNQCKMINEQFEPLVPEGRDIFDVWGNDSNYTKIVAAVDMFFHMFKKHEC
ASFRYGTIVSRFKDCAALATFGHLCKITGMSTEDVTTWILNREVADEMVQ
MMLPGQEIDKADSYMPYLIDFGLSSKSPYSSVKNPAFHFWGQLTALLLRS
TRARNARQPDDIEYTSLTTAGLLYAYAVGSSADLAQQFCVGDNKYTPDDS
TGGLTTNAPPQGRDVVEWLGWFEDQNRKPTPDMMQYAKRAVMSLQGLREK
TIGKYAKSEFDK
Ligand information
>5uk4 Chain w (length=45) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
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Receptor-Ligand Complex Structure
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PDB5uk4 Vesicular stomatitis virus N protein-specific single-domain antibody fragments inhibit replication.
Resolution3.204 Å
Binding residue
(original residue number in PDB)		R143 M149 Y152 K206 Y215 I218 V219 D224 A226 K286 S290 S291 V292 R312 N315 R317 R408
Binding residue
(residue number reindexed from 1)		R133 M139 Y142 K196 Y205 I208 V209 D214 A216 K276 S280 S281 V282 R302 N305 R307 R398
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0005515 protein binding
Biological Process
GO:0019083 viral transcription
GO:0039703 RNA replication
Cellular Component
GO:0019013 viral nucleocapsid
GO:0019029 helical viral capsid
GO:0030430 host cell cytoplasm
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5uk4, PDBe:5uk4, PDBj:5uk4
PDBsum5uk4
PubMed28396572
UniProtP03521|NCAP_VSIVA Nucleoprotein (Gene Name=N)

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