Structure of PDB 5uam Chain B Binding Site BS01

Receptor Information
>5uam Chain B (length=440) Species: 1547444 (Pseudoalteromonas sp. PLSV) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RQVGYFADNGVGNPLAIVQHPAGIHKNGITYVSYQGPKEDPYIASYNHQT
GQWQGPFRAGISELGRRDGGKKFDNHGKPTMLIDDEGYIHIFYGGHGGQA
SNGKNPLGNTHHGANKHAVSKRPYDISQWEDLNNITPFGTYNQAIKMDNG
DIYLFFRHGAHRSDWVYQKSVDNGRTFASPVSFLKHKRRTDIDAVDSWYA
WAGKGQGDNIIVSYDYHVCWDGGAGVNGRGHTTERHDVYFMSFNTKTGEW
SNVEGEKLVLPVTREVADEKTMAMRTGELWTFNGSTHLDAQGQPHIAINA
GIDKGAKTGGPKQTRHVRWNGNEWVGGDKVIPQYERVSRGDFMVTDPENI
RYLTTYNQDNDAVLSWWQSHDGGEHFVEDKTVLRKDNASFAISAFIKDAI
PDAQMLVAEKVSDEGIKMYLVGEEGAVTRSLVDLKTAMPT
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain5uam Chain B Residue 502 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5uam New Ulvan-Degrading Polysaccharide Lyase Family: Structure and Catalytic Mechanism Suggests Convergent Evolution of Active Site Architecture.
Resolution1.45 Å
Binding residue
(original residue number in PDB)		H208 H264 C266 H278
Binding residue
(residue number reindexed from 1)		H161 H217 C219 H231
Annotation score4
Enzymatic activity
Enzyme Commision number 4.2.2.-
Gene Ontology
Molecular Function
GO:0016829 lyase activity
GO:0046872 metal ion binding
Cellular Component
GO:0005886 plasma membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:5uam, PDBe:5uam, PDBj:5uam
PDBsum5uam
PubMed28290654
UniProtA0A1W2VMZ5|UL25_PSEXP Ulvan Lyase-PL25 (Gene Name=PLSV_3936)

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