Structure of PDB 5u4p Chain B Binding Site BS01

Receptor Information
>5u4p Chain B (length=159) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KETVYISSIALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVNVVDVFAMPQ
SGTGVSVEAVDDVFQAKMMDMLKQTGRDQMVVGWYHSHPGFGCWLSSVDV
NTQKSFEQLNSRAVAVVVDPIQSVKGKVVIDAFRLIRHYYSLNIDYHTAK
ETKMLMNLH
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain5u4p Chain B Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5u4p An AAA Motor-Driven Mechanical Switch in Rpn11 Controls Deubiquitination at the 26S Proteasome.
Resolution2.5 Å
Binding residue
(original residue number in PDB)		H109 H111 D122
Binding residue
(residue number reindexed from 1)		H86 H88 D99
Annotation score4
Enzymatic activity
Enzyme Commision number 3.4.19.12: ubiquitinyl hydrolase 1.
Gene Ontology
Molecular Function
GO:0008233 peptidase activity
GO:0008237 metallopeptidase activity

View graph for
Molecular Function
External links
PDB RCSB:5u4p, PDBe:5u4p, PDBj:5u4p
PDBsum5u4p
PubMed28844860
UniProtP43588|RPN11_YEAST Ubiquitin carboxyl-terminal hydrolase RPN11 (Gene Name=RPN11)

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