Structure of PDB 5txe Chain B Binding Site BS01

Receptor Information
>5txe Chain B (length=652) Species: 573065 (Asticcacaulis excentricus CB 48) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
APPVTPEVLVRLADIGTMSASETTPLLSLSPDGRYVAFQVRQADPVTNLN
VFRMVVKATDGATDAIDVDVGGEYLFWTIPSWGYARNAPSGANLTIQPRW
SPSGTHLAYLRQDQGRVRVWRASVKGEGASPVIEDAYDIEDVQWLDDNTL
IYSGRPGFVEAEAEIEREGRRGWVYDERFHPLTGARPRVLEPISIVYQVL
DLKTGTRRAATPTEVARLREKPDPLRAMVGRTTFSVSRTDPQNINAPTTL
VARRGEGEPVRCDEEACQNITRMWGDETANVLYFLRREGWASNEMALYRM
PADALKPVRIWHATGLLQGCERQAKRLICAQESALQPRRLVTLNLTSGQM
SPLYDPNPDLSRYRLPKVERLTLRNRNGIEVFSDLVLPPDYQLGTRLPLV
IVQYSSRGFLRGGTGDENPILPLATAGFAVLSFHSPRSEASYQRFTSPIA
QSKAEYSNWRNRWNILHTLEDLIDDLDRRGVIDPARVGLTGLADGATTVH
FGLINSHRFAAAVTSSCCTDSFTASVMNGPRISGALKAYGIETDQADDGP
FWAATSFVVNASRLDTPLLIQSADEEYLGALPGFTALQQARKPVELIIYP
NEHHVKWQPAHRLAVYNRTIDWFRFWLMDQSDPAPDKAAQYDRWRALRAL
RQ
Ligand information
>5txe Chain D (length=18) Species: 573065 (Asticcacaulis excentricus CB 48) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
GPTPMVGLDSVSGQYWDQ
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5txe Structure of the Lasso Peptide Isopeptidase Identifies a Topology for Processing Threaded Substrates.
Resolution2.2 Å
Binding residue
(original residue number in PDB)		S53 W111 I113 S115 W116 S124 A126 H214 L216 Y438 A527 N562 Y573 H638
Binding residue
(residue number reindexed from 1)		S19 W77 I79 S81 W82 S90 A92 H180 L182 Y404 A493 N528 Y539 H604
Enzymatic activity
Enzyme Commision number 3.4.-.-
Gene Ontology
Molecular Function
GO:0008236 serine-type peptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:5txe, PDBe:5txe, PDBj:5txe
PDBsum5txe
PubMed27998080
UniProtE8RUP5|ATXE2_ASTEC Lasso peptide isopeptidase AtxE2 (Gene Name=atxE2)

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