Structure of PDB 5tq2 Chain B Binding Site BS01

Receptor Information
>5tq2 Chain B (length=335) Species: 10116 (Rattus norvegicus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LNIAVLLGHSHDVTEREVNVVALLMNRTDPKSLITHVCDLMSGARIHGLV
FGDDTDQEAVAQMLDFISSQTFIPILGIHGGASMIMADKDPTSTFFQFGA
SIQQQATVMLKIMQDYDWHVFSLVTTIFPGYRDFISFIKTTVDNSFVGWD
MQNVITLDTSFEDAKTQVQLKKIHSSVILLYCSKDEAVLILSEARSLGLT
GYDFFWIVPSLVSGNTELIPKEFPSGLISVSYDDWDYSLEARVRDGLGIL
TTAASSMLEKFSYIPEAKASCYGQPLHTLHQFMVNVTWDGKDLSFTEEGY
QVHPRLVVIVLNKDREWEKVGKWENQTLSLRHAVW
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain5tq2 Chain B Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5tq2 Molecular Basis for Subtype Specificity and High-Affinity Zinc Inhibition in the GluN1-GluN2A NMDA Receptor Amino-Terminal Domain.
Resolution3.289 Å
Binding residue
(original residue number in PDB)		H44 H128 E266 D282
Binding residue
(residue number reindexed from 1)		H11 H79 E217 D233
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:5tq2, PDBe:5tq2, PDBj:5tq2
PDBsum5tq2
PubMed27916457
UniProtQ00959|NMDE1_RAT Glutamate receptor ionotropic, NMDA 2A (Gene Name=Grin2a)

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