Structure of PDB 5tn1 Chain B Binding Site BS01
Receptor Information
>5tn1 Chain B (length=245) Species:
9606
(Homo sapiens) [
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NSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRE
LVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLL
FAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIIL
LNSGVYTFSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLA
QLLLILSHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHRLH
Ligand information
>5tn1 Chain D (length=11) Species:
9606
(Homo sapiens) [
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HKILHRLLQDS
Receptor-Ligand Complex Structure
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PDB
5tn1
Systems Structural Biology Analysis of Ligand Effects on ER alpha Predicts Cellular Response to Environmental Estrogens and Anti-hormone Therapies.
Resolution
2.055 Å
Binding residue
(original residue number in PDB)
I358 K362 L372 Q375 V376 E380 D538 L539 E542
Binding residue
(residue number reindexed from 1)
I55 K59 L69 Q72 V73 E77 D233 L234 E237
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5tn1
,
PDBe:5tn1
,
PDBj:5tn1
PDBsum
5tn1
PubMed
28042045
UniProt
P03372
|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)
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