Structure of PDB 5tmw Chain B Binding Site BS01
Receptor Information
>5tmw Chain B (length=240) Species:
9606
(Homo sapiens) [
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SLALSLTADQMVSALLDAEPPILYSEYDPFSEASMMGLLTNLADRELVHM
INWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPN
LLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSG
VYTFLTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLL
ILSHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHRL
Ligand information
>5tmw Chain D (length=10) Species:
9606
(Homo sapiens) [
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HKILHRLLQD
Receptor-Ligand Complex Structure
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PDB
5tmw
Systems Structural Biology Analysis of Ligand Effects on ER alpha Predicts Cellular Response to Environmental Estrogens and Anti-hormone Therapies.
Resolution
2.286 Å
Binding residue
(original residue number in PDB)
I358 L372 Q375 V376 L379 E380 L539 E542
Binding residue
(residue number reindexed from 1)
I51 L65 Q68 V69 L72 E73 L230 E233
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5tmw
,
PDBe:5tmw
,
PDBj:5tmw
PDBsum
5tmw
PubMed
28042045
UniProt
P03372
|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)
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