Structure of PDB 5tmv Chain B Binding Site BS01
Receptor Information
>5tmv Chain B (length=239) Species:
9606
(Homo sapiens) [
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NSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRE
LVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLL
FAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIIL
LNSGVYTFTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQ
LLLILSHIRHMSNKGMEHLYSMKCVPLSDLLLEMLDAHR
Ligand information
>5tmv Chain D (length=10) Species:
9606
(Homo sapiens) [
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KILHRLLQDS
Receptor-Ligand Complex Structure
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PDB
5tmv
Systems Structural Biology Analysis of Ligand Effects on ER alpha Predicts Cellular Response to Environmental Estrogens and Anti-hormone Therapies.
Resolution
2.38 Å
Binding residue
(original residue number in PDB)
I358 K362 L372 H373 Q375 V376 L379 D538 L539 E542
Binding residue
(residue number reindexed from 1)
I55 K59 L69 H70 Q72 V73 L76 D229 L230 E233
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5tmv
,
PDBe:5tmv
,
PDBj:5tmv
PDBsum
5tmv
PubMed
28042045
UniProt
P03372
|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)
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