Structure of PDB 5tms Chain B Binding Site BS01
Receptor Information
>5tms Chain B (length=243) Species:
9606
(Homo sapiens) [
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KKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLAD
RELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK
LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSI
ILLNSGVYTTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLA
QLLLILSHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHR
Ligand information
>5tms Chain D (length=10) Species:
9606
(Homo sapiens) [
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KILHRLLQDS
Receptor-Ligand Complex Structure
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PDB
5tms
Systems Structural Biology Analysis of Ligand Effects on ER alpha Predicts Cellular Response to Environmental Estrogens and Anti-hormone Therapies.
Resolution
2.24 Å
Binding residue
(original residue number in PDB)
I358 K362 L372 Q375 V376 L379 E380 D538 L539 E542
Binding residue
(residue number reindexed from 1)
I57 K61 L71 Q74 V75 L78 E79 D233 L234 E237
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5tms
,
PDBe:5tms
,
PDBj:5tms
PDBsum
5tms
PubMed
28042045
UniProt
P03372
|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)
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