Structure of PDB 5tmo Chain B Binding Site BS01
Receptor Information
>5tmo Chain B (length=239) Species:
9606
(Homo sapiens) [
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SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL
VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLF
APNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILL
NSGVYTFKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLL
ILSHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHR
Ligand information
>5tmo Chain D (length=11) Species:
9606
(Homo sapiens) [
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HKILHRLLQDS
Receptor-Ligand Complex Structure
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PDB
5tmo
Systems Structural Biology Analysis of Ligand Effects on ER alpha Predicts Cellular Response to Environmental Estrogens and Anti-hormone Therapies.
Resolution
2.172 Å
Binding residue
(original residue number in PDB)
I358 K362 L372 Q375 V376 E380 D538 L539 E542
Binding residue
(residue number reindexed from 1)
I54 K58 L68 Q71 V72 E76 D229 L230 E233
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5tmo
,
PDBe:5tmo
,
PDBj:5tmo
PDBsum
5tmo
PubMed
28042045
UniProt
P03372
|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)
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