Structure of PDB 5tmm Chain B Binding Site BS01
Receptor Information
>5tmm Chain B (length=222) Species:
9606
(Homo sapiens) [
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SLALSLTADQMVSALLDAEPPILYSEYPFSEASMMGLLTNLADRELVHMI
NWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNL
LLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGV
YTKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSN
KGMEHLYSMKSDLLLEMLDAHR
Ligand information
>5tmm Chain D (length=9) Species:
9606
(Homo sapiens) [
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KILHRLLQD
Receptor-Ligand Complex Structure
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PDB
5tmm
Systems Structural Biology Analysis of Ligand Effects on ER alpha Predicts Cellular Response to Environmental Estrogens and Anti-hormone Therapies.
Resolution
2.2 Å
Binding residue
(original residue number in PDB)
I358 K362 L372 V376 E542 M543
Binding residue
(residue number reindexed from 1)
I50 K54 L64 V68 E216 M217
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5tmm
,
PDBe:5tmm
,
PDBj:5tmm
PDBsum
5tmm
PubMed
28042045
UniProt
P03372
|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)
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