Structure of PDB 5tml Chain B Binding Site BS01
Receptor Information
>5tml Chain B (length=241) Species:
9606
(Homo sapiens) [
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SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL
VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLF
APNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILL
NSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRL
AQLLLILSHIRHMSNKGMEHLYSMKCKNLSDLLLEMLDAHR
Ligand information
>5tml Chain D (length=11) Species:
9606
(Homo sapiens) [
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HKILHRLLQDS
Receptor-Ligand Complex Structure
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PDB
5tml
Systems Structural Biology Analysis of Ligand Effects on ER alpha Predicts Cellular Response to Environmental Estrogens and Anti-hormone Therapies.
Resolution
2.25 Å
Binding residue
(original residue number in PDB)
I358 K362 L372 V376 E380 D538 L539 E542
Binding residue
(residue number reindexed from 1)
I54 K58 L68 V72 E76 D231 L232 E235
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5tml
,
PDBe:5tml
,
PDBj:5tml
PDBsum
5tml
PubMed
28042045
UniProt
P03372
|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)
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