Structure of PDB 5tm8 Chain B Binding Site BS01
Receptor Information
>5tm8 Chain B (length=228) Species:
9606
(Homo sapiens) [
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NSLALSLTADQMVSALLDAEPPILYSEYPFSEASMMGLLTNLADRELVHM
INWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPN
LLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSG
VYTFKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHM
SNKGMEHLYSMKVVPLSDLLLEMLDAHR
Ligand information
>5tm8 Chain D (length=10) Species:
9606
(Homo sapiens) [
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HKILHRLLQD
Receptor-Ligand Complex Structure
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PDB
5tm8
Systems Structural Biology Analysis of Ligand Effects on ER alpha Predicts Cellular Response to Environmental Estrogens and Anti-hormone Therapies.
Resolution
1.99 Å
Binding residue
(original residue number in PDB)
I358 K362 L372 V376 E380 L539 E542
Binding residue
(residue number reindexed from 1)
I51 K55 L65 V69 E73 L219 E222
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5tm8
,
PDBe:5tm8
,
PDBj:5tm8
PDBsum
5tm8
PubMed
28042045
UniProt
P03372
|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)
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