Structure of PDB 5tm7 Chain B Binding Site BS01
Receptor Information
>5tm7 Chain B (length=240) Species:
9606
(Homo sapiens) [
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SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL
VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLF
APNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILL
NSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRL
AQLLLILSHIRHMSNKGMEHLYSMKCKLSDLLLEMLDAHR
Ligand information
>5tm7 Chain D (length=11) Species:
9606
(Homo sapiens) [
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HKILHRLLQDS
Receptor-Ligand Complex Structure
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PDB
5tm7
Systems Structural Biology Analysis of Ligand Effects on ER alpha Predicts Cellular Response to Environmental Estrogens and Anti-hormone Therapies.
Resolution
2.4 Å
Binding residue
(original residue number in PDB)
I358 K362 L372 V376 L379 E380 D538 E542
Binding residue
(residue number reindexed from 1)
I54 K58 L68 V72 L75 E76 D230 E234
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5tm7
,
PDBe:5tm7
,
PDBj:5tm7
PDBsum
5tm7
PubMed
28042045
UniProt
P03372
|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)
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