Structure of PDB 5tm2 Chain B Binding Site BS01
Receptor Information
>5tm2 Chain B (length=231) Species:
9606
(Homo sapiens) [
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ALSLTADQMVSALLDAEPPILYSEYDPTRPSEASMMGLLTNLADRELVHM
INWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPN
LLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSG
VYTFSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSH
IRHMSNKGMEHLYSMKCKNVLSDLLLEMLDA
Ligand information
>5tm2 Chain D (length=9) Species:
9606
(Homo sapiens) [
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KILHRLLQD
Receptor-Ligand Complex Structure
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PDB
5tm2
Systems Structural Biology Analysis of Ligand Effects on ER alpha Predicts Cellular Response to Environmental Estrogens and Anti-hormone Therapies.
Resolution
2.603 Å
Binding residue
(original residue number in PDB)
I358 K362 V376 D538 L539 E542 M543
Binding residue
(residue number reindexed from 1)
I51 K55 V69 D223 L224 E227 M228
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5tm2
,
PDBe:5tm2
,
PDBj:5tm2
PDBsum
5tm2
PubMed
28042045
UniProt
P03372
|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)
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