Structure of PDB 5tlx Chain B Binding Site BS01
Receptor Information
>5tlx Chain B (length=242) Species:
9606
(Homo sapiens) [
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SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL
VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLF
APNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILL
NSGVYTFSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQ
LLLILSHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHR
Ligand information
>5tlx Chain D (length=10) Species:
9606
(Homo sapiens) [
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KILHRLLQDS
Receptor-Ligand Complex Structure
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PDB
5tlx
Systems Structural Biology Analysis of Ligand Effects on ER alpha Predicts Cellular Response to Environmental Estrogens and Anti-hormone Therapies.
Resolution
2.103 Å
Binding residue
(original residue number in PDB)
I358 L372 V376 E380 D538 L539 E542
Binding residue
(residue number reindexed from 1)
I54 L68 V72 E76 D232 L233 E236
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5tlx
,
PDBe:5tlx
,
PDBj:5tlx
PDBsum
5tlx
PubMed
28042045
UniProt
P03372
|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)
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