Structure of PDB 5tlt Chain B Binding Site BS01
Receptor Information
>5tlt Chain B (length=240) Species:
9606
(Homo sapiens) [
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SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL
VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLF
APNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILL
NSGVYTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLL
ILSHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHRL
Ligand information
>5tlt Chain D (length=9) Species:
9606
(Homo sapiens) [
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KILHRLLQD
Receptor-Ligand Complex Structure
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PDB
5tlt
Systems Structural Biology Analysis of Ligand Effects on ER alpha Predicts Cellular Response to Environmental Estrogens and Anti-hormone Therapies.
Resolution
1.903 Å
Binding residue
(original residue number in PDB)
I358 K362 L372 V376 L379 E380 D538 L539 E542 M543
Binding residue
(residue number reindexed from 1)
I54 K58 L68 V72 L75 E76 D229 L230 E233 M234
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5tlt
,
PDBe:5tlt
,
PDBj:5tlt
PDBsum
5tlt
PubMed
28042045
UniProt
P03372
|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)
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