Structure of PDB 5tll Chain B Binding Site BS01

Receptor Information
>5tll Chain B (length=234) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SLALSLTADQMVSALLDAEPPILYSEYPTRPFSEASMMGLLTNLADRELV
HMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFA
PNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLN
SGVYTEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHI
RHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHR
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5tll Systems Structural Biology Analysis of Ligand Effects on ER alpha Predicts Cellular Response to Environmental Estrogens and Anti-hormone Therapies.
Resolution2.423 Å
Binding residue
(original residue number in PDB)
I358 K362 L372 V376 E380 E542
Binding residue
(residue number reindexed from 1)
I53 K57 L67 V71 E75 E228
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:5tll, PDBe:5tll, PDBj:5tll
PDBsum5tll
PubMed28042045
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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