Structure of PDB 5tlg Chain B Binding Site BS01
Receptor Information
>5tlg Chain B (length=236) Species:
9606
(Homo sapiens) [
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SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL
VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLF
APNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILL
NSGVYTFEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILS
HIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHR
Ligand information
>5tlg Chain D (length=9) Species:
9606
(Homo sapiens) [
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KILHRLLQD
Receptor-Ligand Complex Structure
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PDB
5tlg
Systems Structural Biology Analysis of Ligand Effects on ER alpha Predicts Cellular Response to Environmental Estrogens and Anti-hormone Therapies.
Resolution
2.228 Å
Binding residue
(original residue number in PDB)
I358 K362 V376 D538 L539 E542
Binding residue
(residue number reindexed from 1)
I54 K58 V72 D226 L227 E230
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5tlg
,
PDBe:5tlg
,
PDBj:5tlg
PDBsum
5tlg
PubMed
28042045
UniProt
P03372
|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)
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