Structure of PDB 5tld Chain B Binding Site BS01
Receptor Information
>5tld Chain B (length=235) Species:
9606
(Homo sapiens) [
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SLALSLTADQMVSALLDAEPPILYSEYDPTRPSEASMMGLLTNLADRELV
HMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFA
PNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLN
SGVYTSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILS
HIRHMSNKGMEHLYSMKCKVVPLSDLLLEMLDAHR
Ligand information
>5tld Chain D (length=9) Species:
9606
(Homo sapiens) [
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KILHRLLQD
Receptor-Ligand Complex Structure
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PDB
5tld
Systems Structural Biology Analysis of Ligand Effects on ER alpha Predicts Cellular Response to Environmental Estrogens and Anti-hormone Therapies.
Resolution
2.375 Å
Binding residue
(original residue number in PDB)
I358 K362 L372 V376 L379 E380 D538 L539 E542
Binding residue
(residue number reindexed from 1)
I53 K57 L67 V71 L74 E75 D225 L226 E229
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5tld
,
PDBe:5tld
,
PDBj:5tld
PDBsum
5tld
PubMed
28042045
UniProt
P03372
|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)
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